As long as you are not running bootcamp, it should not be a factor.
Also, for your Mac partition, how much free space is on it? That would be the important thing in terms of using Mac software (again, assuming bootcamp is not running).
Again, cannot stress enough the need for backups. I suspect that on this site, it's similar to the sentiment on other sites. Time Machine is OK, it comes with the Mac OS, and it's free (as far as I know, the version with Catalina is fine). The other two I already mentioned: SuperDuper! (I use it, it's free, and there is a paid version (as are upgrades; I paid for it a few years ago, and it's well wroth it):
Note that it is not yet compatible with Big Sur.
The other excellent one is Carbon Copy Cloner:
It is not free, and upgrades are also not free. They have released a beta version that is compatible with Big Sur, but for me, a backup program is just too, too important to use, and thus I would not use a beta version of it. (I have 4 other critical programs that are not yet compatible).
As for disk cleanup/maintenance/repairs, there are some excellent free and commercial programs available to help you witn that. One of them is Onyx:
OnyX is a multifunction utility that you can use to verify the startup disk and the structure of its system files; run tasks of cleaning and computer maintenance; configure some hidden parameters of many Apple applications; and more.
I've been using it for a number of years, and rely on it. It has been around for a number of years, is a solid, reliable performer, and is free. Note that there are specific versions fo each Mac OS. And like SuperDuper!, it is not yet compatible with Big Sur.
The other one I use is a commercial program entitled Tech Tool Pro:
Techtool Pro is Mac utility software for maintaining and troubleshooting your Mac, including drive repair, RAM testing, and more.
The comments I made above about Onyx apply equally well to Tech Tool Pro.
Then, of course, you can do some disk cleanup (maybe a good amount) on your own.