URGENT! my programs keep crashing!

Hey guys
I'm trying to do some design work on my macbook and nearly all the programs crash after opening up or begining to open. Then, the pop-up for a crash report comes up. Everytime! I've cleared up loads of memory in case that was slowing them down but there's no change. I have a deadline for this work and am in a foreign country with little available resources as I am constantly travelling...Please Help, any suggestions would be greatly appreciated.
thanks again,
Lu

*) Create a NEW account on your Mac if possible and test logging in and opening a few apps there and see how that works out?

In my blog link in my signature I have posted a few suggestions as well.

Let us know how it goes?